Which adverse effect is listed for methylprednisolone in the following options?

• A. Fatigue
• B. Diarrhea
• C. Sort throat
• D. Weight loss

Answer: (C)

Systemic corticosteroids like methylprednisolone suppress the immune system, so they can increase the risk of infections. A sore throat can be an early sign of an infection, which makes it a plausible adverse effect listed for this drug. Fatigue and diarrhea aren’t typical direct adverse effects of systemic methylprednisolone, and weight loss is not expected—steroids more often cause weight gain and fluid retention. So sore throat best matches the drug’s adverse effect profile.