What is serotonin syndrome and which drug combinations commonly cause it?

• A. A mild allergic reaction.
• B. Serotonin syndrome is a mood disorder.
• C. Potentially life-threatening hyperthermia, agitation, hyperreflexia; due to combinations of SSRIs with MAO inhibitors or SNRIs or tricyclics; discontinue and provide supportive care.
• D. A withdrawal syndrome.

Answer: (C)