List two major adverse effects of opioids beyond respiratory depression and one patient education point.

• A. Constipation and sedation; educate to use bowel regimen, avoid alcohol, and safety with activities.
• B. Nausea and sweating; avoid caffeine.
• C. Hyperactivity and insomnia; monitor BP.
• D. Headache and dizziness; avoid lying down.

Answer: (B)