ACE inhibitors commonly cause cough and hyperkalemia. Explain why and what monitoring is essential.

• A. Cough from bradykinin accumulation; hyperkalemia from reduced aldosterone; monitor potassium and kidney function; counsel on potential cough.
• B. Cough from prostaglandin release; hyperkalemia from increased aldosterone.
• C. Cough due to histamine release; hyperkalemia due to potassium supplementation.
• D. Cough due to glucose changes; hyperkalemia due to kidney injury.

Answer: (A)